Synthesis of β-Amino Alcohols via the Reduction of Lactamides Derived from Ethyl (2S)-Lactate with Borane-Methyl Sulfide
Synlett
DOI: 10.1055/s-0029-1217538
Abstract
Reactions of ethyl (2)-lactate with
various amines affords lactamides that are reduced with borane-methyl
sulfide in the presence of boron trifluoride etherate to generate
enantiomerically pure β-amino alcohols in good yield.
[...]
© Georg Thieme Verlag Stuttgart ˙ New York
Get connected:
Table of contents | Abstract | Full text
