Benzylic Brominations with N-Bromosuccinimide in (Trifluoromethyl)benzene
Synthesis
DOI: 10.1055/s-0029-1216793
Abstract
A variety of benzylic brominations were performed by using -bromosuccinimide in (trifluoromethyl)benzene
with photochemical activation in the presence of 2,2′-azobisisobutyronitrile, 1,1′-azobis(cyclohexanecarbonitrile),
or benzoyl peroxide as the radical initiator. This system provides
clean, rapid, and high-yielding reactions with replacement of conventional
solvents, such as tetrachloromethane, by less-toxic (trifluoromethyl)benzene.
[...]
© Georg Thieme Verlag Stuttgart ˙ New York
Get connected:
Table of contents | Abstract | Full text
